Hanscom Air Force Base (AFB) (IATA: BED, ICAO: KBED, FAA LID: BED) is a United States Air Force base located predominantly within Bedford, Massachusetts, with portions extending into the adjoining towns of Concord and Lincoln. The facility is adjacent to Hanscom Field which provides general aviation and charter service.

Hanscom AFB is the part of the Air Force Life Cycle Management Center, one of five centers under Air Force Materiel Command (AFMC). The Air Force Life Cycle Management Center is the single center responsible for total life cycle management of Air Force weapon systems and is headquartered at Wright-Patterson AFB, Ohio. The host unit at Hanscom is the 66th Air Base Group (66 ABG) assigned to AFMC.