Naval Hospital Beaufort is a United States Navy hospital located in Port Royal, South Carolina. Commissioned on April 29, 1949, the hospital is one of only a handful of its kind that sits within its own complex rather than within a larger base. It takes its name from Beaufort, the larger community north of Port Royal that is commonly associated with military installations in the Lowcountry region.

NH Beaufort serves nearby Marine Corps bases MCRD Parris Island and MCAS Beaufort, including the housing area of Laurel Bay.